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- Relationship between endogenous sex hormone ranges, lipoproteins and coronary atherosclerosis in males present process coronary angiography.
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac threat elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, likely secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the best coronary artery. Physicians and sufferers should concentrate on the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a component of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity.
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In addition, the info available in the literature does not account for the steroid type or dose, as neither could additionally be recognized. Patients also could also be taking concomitant stimulants, similar to ephedra, which might confound knowledge and the potential for antagonistic events. It is likely that the frequency of cardiac occasions is underreported within the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which embrace greater than 30 natural and artificial derivatives of testosterone, might trigger a large spectrum of medical sequalae.
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